ionis pharmaceuticals inc. - IONS

IONS

Close Chg Chg %
28.68 -0.30 -1.05%

Closed Market

28.38

-0.30 (1.05%)

Volume: 1.52M

Last Updated:

Apr 15, 2025, 4:00 PM EDT

Company Overview: ionis pharmaceuticals inc. - IONS

IONS Key Data

Open

$28.62

Day Range

28.16 - 28.97

52 Week Range

23.95 - 52.34

Market Cap

$4.44B

Shares Outstanding

158.97M

Public Float

154.59M

Beta

0.29

Rev. Per Employee

N/A

P/E Ratio

N/A

EPS

-$3.04

Yield

0.00%

Dividend

N/A

EX-DIVIDEND DATE

SHORT INTEREST

N/A

AVERAGE VOLUME

1.90M

 

IONS Performance

1 Week
 
1.72%
 
1 Month
 
-13.90%
 
3 Months
 
-9.70%
 
1 Year
 
-30.24%
 
5 Years
 
-48.47%
 

IONS Analyst Ratings

  • Sell
  • Under
  • Hold
  • Over
  • Buy
Number of Ratings 27
Full Ratings ➔

About ionis pharmaceuticals inc. - IONS

Ionis Pharmaceuticals, Inc. engages in the development and commercialization of human therapeutic drugs using antisense technology. The company was founded by Stanley T. Crooke, David J. Ecker, Christopher K. Mirabelli, and Brett P. Monia on January 10, 1989 and is headquartered in Carlsbad, CA.

IONS At a Glance

Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, California 92010
Phone 1-760-931-9200 Revenue 705.14M
Industry Pharmaceuticals: Major Net Income -453,897,000.00
Sector Health Technology Employees 1,069
Fiscal Year-end 12 / 2025
View SEC Filings

IONS Valuation

P/E Current N/A
P/E Ratio (with extraordinary items) N/A
P/E Ratio (without extraordinary items) N/A
Price to Sales Ratio 7.413
Price to Book Ratio 9.383
Price to Cash Flow Ratio N/A
Enterprise Value to EBITDA -10.777
Enterprise Value to Sales 6.925
Total Debt to Enterprise Value 0.401

IONS Efficiency

Revenue/Employee 659,623.948
Income Per Employee -424,599.626
Receivables Turnover 7.649
Total Asset Turnover 0.235

IONS Liquidity

Current Ratio 8.471
Quick Ratio 8.431
Cash Ratio 7.445

IONS Profitability

Gross Margin 95.291
Operating Margin -67.374
Pretax Margin -65.245
Net Margin -64.37
Return on Assets -15.146
Return on Equity -93.104
Return on Total Capital -17.82
Return on Invested Capital -18.761

IONS Capital Structure

Total Debt to Total Equity 332.927
Total Debt to Total Capital 76.901
Total Debt to Total Assets 65.213
Long-Term Debt to Equity 331.35
Long-Term Debt to Total Capital 76.537
  • Income Statement
  • Balance Sheet
  • Cash Flow Statement

Annual Financials for Ionis Pharmaceuticals Inc. - IONS

Collapse All in section
All values USD millions. 2021 2022 2023 2024 5-year trend
Sales/Revenue
810.46M 587.37M 787.65M 705.14M
Sales Growth
+11.13% -27.53% +34.10% -10.48%
Cost of Goods Sold (COGS) incl D&A
30.40M 36.22M 31.63M 33.20M
COGS excluding D&A
- - - -
-
Depreciation & Amortization Expense
19.56M 22.11M 22.50M 21.99M
Depreciation
17.21M 19.69M 19.94M 19.65M
Amortization of Intangibles
2.35M 2.42M 2.56M 2.34M
COGS Growth
+4.45% +19.14% -12.67% +4.98%
Gross Income
780.05M 551.15M 756.02M 671.93M
Gross Income Growth
+11.41% -29.35% +37.17% -11.12%
Gross Profit Margin
+96.25% +93.83% +95.98% +95.29%
2021 2022 2023 2024 5-year trend
SG&A Expense
810.24M 961.34M 1.11B 1.15B
Research & Development
643.45M 833.15M 899.63M 901.53M
Other SG&A
166.79M 128.19M 210.12M 245.48M
SGA Growth
-7.11% +18.65% +15.44% +3.36%
Other Operating Expense
- - - -
-
Unusual Expense
(1.48M) 7.33M (11.49M) 2.89M
EBIT after Unusual Expense
(28.71M) (417.52M) (342.24M) (477.97M)
Non Operating Income/Expense
8.91M 167.66M 89.74M 108.35M
Non-Operating Interest Income
10.04M 25.33M 89.04M 107.02M
Equity in Earnings of Affiliates
- - - -
-
Interest Expense
9.35M 8.12M 81.46M 90.45M
Interest Expense Growth
-79.22% -13.12% +902.92% +11.04%
Gross Interest Expense
9.35M 8.12M 81.46M 90.45M
Interest Capitalized
- - - -
-
Pretax Income
(29.15M) (257.99M) (333.96M) (460.07M)
Pretax Income Growth
+82.86% -785.09% -29.45% -37.76%
Pretax Margin
-3.60% -43.92% -42.40% -65.25%
Income Tax
(551.00K) 11.74M 32.32M (6.17M)
Income Tax - Current - Domestic
(890.00K) 11.65M 32.17M (6.34M)
Income Tax - Current - Foreign
339.00K 86.00K 147.00K 169.00K
Income Tax - Deferred - Domestic
- - - -
-
Income Tax - Deferred - Foreign
- - - -
-
Income Tax Credits
- - - -
-
Equity in Earnings of Affiliates
- - - -
-
Other After Tax Income (Expense)
- - - -
-
Consolidated Net Income
(28.60M) (269.72M) (366.29M) (453.90M)
Minority Interest Expense
- - - -
-
Net Income
(28.60M) (269.72M) (366.29M) (453.90M)
Net Income Growth
+93.67% -843.18% -35.80% -23.92%
Net Margin Growth
-3.53% -45.92% -46.50% -64.37%
Extraordinaries & Discontinued Operations
- - - -
-
Discontinued Operations
- - - -
-
Net Income After Extraordinaries
(28.60M) (269.72M) (366.29M) (453.90M)
Preferred Dividends
- - - -
-
Net Income Available to Common
(28.60M) (269.72M) (366.29M) (453.90M)
EPS (Basic)
-0.2028 -1.9015 -2.558 -3.0358
EPS (Basic) Growth
+93.73% -837.62% -34.53% -18.68%
Basic Shares Outstanding
141.02M 141.85M 143.19M 149.51M
EPS (Diluted)
-0.2028 -1.9015 -2.558 -3.0358
EPS (Diluted) Growth
+93.73% -837.62% -34.53% -18.68%
Diluted Shares Outstanding
141.02M 141.85M 143.19M 149.51M
EBITDA
(10.63M) (388.09M) (331.23M) (453.09M)
EBITDA Growth
+93.14% -3,552.23% +14.65% -36.79%
EBITDA Margin
-1.31% -66.07% -42.05% -64.26%

Snapshot

Average Recommendation OVERWEIGHT Average Target Price 56.00
Number of Ratings 27 Current Quarters Estimate -0.991
FY Report Date 06 / 2025 Current Year's Estimate -3.817
Last Quarter’s Earnings -1.04 Median PE on CY Estimate N/A
Year Ago Earnings -3.04 Next Fiscal Year Estimate -3.001
Median PE on Next FY Estimate N/A

Earnings Per Share

This Quarter Next Quarter This Fiscal Next Fiscal
# of Estimates 15 14 19 20
Mean Estimate -0.99 -0.88 -3.82 -3.00
High Estimates -0.80 -0.68 -3.26 -2.11
Low Estimate -1.16 -1.07 -4.29 -3.76
Coefficient of Variance -11.56 -13.22 -8.36 -15.15

Analysts Recommendations

Current 1 Month Ago 3 Months Ago
BUY 17 16 17
OVERWEIGHT 1 1 1
HOLD 8 8 6
UNDERWEIGHT 0 0 0
SELL 1 1 1
MEAN Overweight Overweight Overweight

Insider Actions for Ionis Pharmaceuticals Inc. - IONS

Date Name Shares Transaction Value
Mar 14, 2025 Brett P. Monia Chief Executive Officer; Director 180,980 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $32.32 per share 5,849,273.60
Feb 7, 2025 Patrick R. O'Neil EVP CLO & General Counsel 57,452 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $31.62 per share 1,816,632.24
Jul 18, 2024 Joseph Loscalzo Director 4,079 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 Allene M. Diaz Director 15,716 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $50.17 per share 788,471.72
Jul 18, 2024 Spencer R. Berthelsen Director 4,079 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 Allene M. Diaz Director 4,079 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 Spencer R. Berthelsen Director 151,934 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 Joseph H. Wender Director 4,079 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 Joseph H. Wender Director 132,756 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 B. Lynne Parshall Director 4,079 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 B. Lynne Parshall Director 87,265 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 Joseph R. Klein Director N/A Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 Allene M. Diaz Director 16,453 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $48.94 per share 805,209.82
Jul 18, 2024 Allene M. Diaz Director 17,353 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 Joseph R. Klein Director N/A Open market or private sale of non-derivative or derivative security Non-derivative transaction at $50 per share 0.00
Jul 18, 2024 Joseph R. Klein Director 12,000 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 Non-derivative transaction at $24.42 per share 293,040.00
Jul 18, 2024 Joan Elizabeth Herman Director 4,079 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 Joan Elizabeth Herman Director 42,007 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 18, 2024 Joseph Loscalzo Director 45,759 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Jul 4, 2024 Michael R. Hayden Director 10,111 Grant, award or other acq pursuant to Rule 16b-3(d) 0.00

Ionis Pharmaceuticals Inc. in the News